People
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Shawna joined the Lowe lab in summer of 2020 as a postdoctoral fellow. She received her Ph.D. |
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Shawna joined the Lowe lab in summer of 2020 as a postdoctoral fellow. She received her Ph.D. |
Molecular and Cellular Biology (MCB) 7-218
420 Washington Ave SE
Minneapolis, MN 55455
Lab phone number: 612-625-5022
Lab Manager: Mara Supik [email protected]
Le G, Baumann CW, Warren GL, Lowe DA (2023). In vivo potentiation of muscle torque is enhanced in female mice through estradiol-estrogen receptor signaling. J Appl Physiol (1985). Online ahead of print. PMID: 36735234.
Peyton MP, Tzu-Yi Y, Higgins L, Markowski TW, Vue C, Parker LL, Lowe DA (2022). Global phosphoproteomic profiling of skeletal muscle in ovarian-hormone deficient mice. Physiol Genomics 54 (11):417-432. PMID 36062884.
Dr. Lowe’s laboratory investigates cellular and molecular mechanisms underlying skeletal muscle deterioration that occur with age, injury, and disease. We are particularly interested in how the loss of estradiol causes muscle weakness and impaired regeneration of injured muscles. Our studies point toward the deterioration of myosin function and satellite cells as two of the culprits. We are highly collaborative in muscular dystrophy research having published with eight other UMN muscle biologists.